BDBM50485 2-[[5,6-bis(2-furanyl)-1,2,4-triazin-3-yl]thio]-1-(4-methoxyphenyl)ethanone::2-[[5,6-bis(2-furyl)-1,2,4-triazin-3-yl]thio]-1-(4-methoxyphenyl)ethanone::2-[[5,6-bis(furan-2-yl)-1,2,4-triazin-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone::CHEMBL1349474::MLS000678396::SMR000284980::cid_6403001

SMILES COc1ccc(cc1)C(=O)CSc1nnc(-c2ccco2)c(n1)-c1ccco1

InChI Key InChIKey=QYWTZJSMNORGMR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50485   

TargetProstaglandin E synthase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50485(SMR000284980 | 2-[[5,6-bis(2-furanyl)-1,2,4-triazi...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPC4 and SFRS1-interacting protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50485(SMR000284980 | 2-[[5,6-bis(2-furanyl)-1,2,4-triazi...)
Affinity DataIC50: 6.45E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2014
Entry Details
PCBioAssay
LigandPNGBDBM50485(SMR000284980 | 2-[[5,6-bis(2-furanyl)-1,2,4-triazi...)
Affinity DataIC50: 6.58E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetPC4 and SFRS1-interacting protein(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50485(SMR000284980 | 2-[[5,6-bis(2-furanyl)-1,2,4-triazi...)
Affinity DataIC50: 5.37E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2014
Entry Details
PCBioAssay