BDBM50486046 CHEMBL2204519

SMILES C[C@H](NC(=O)c1ccc(N2C3CCC2CC(NC(=O)c2ccc(C(N)=O)c(NC4CCC4)c2)C3)nc1)c1ccc(N2CCN(C)CC2)cc1

InChI Key InChIKey=DMWFRFVIEAWZAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50486046   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486046BDBM50486046(CHEMBL2204519)
Affinity DataIC50: 59nMAssay Description:Inhibition of Hsp90 in human A549 cells assessed as Raf1 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Exelixis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486046BDBM50486046(CHEMBL2204519)
Affinity DataIC50: 160nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed