BDBM50490611 CHEMBL2337604

SMILES [H][C@@]1(CCNC1)[C@@H](Oc1ccc(Cl)cc1Cl)c1ccccc1

InChI Key InChIKey=DRRQCYGCMNHHQK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50490611   

TargetSodium-dependent noradrenaline transporter(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50490611(CHEMBL2337604)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant NET expressed in HEK293 cells assessed as inhibition of [3H]NE reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50490611(CHEMBL2337604)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant SERT expressed in HEK293 cells assessed as inhibition of [3H]5HT reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50490611(CHEMBL2337604)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]WIN35428 from human recombinant DAT transfected in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed