BDBM50490697 CHEMBL2336821

SMILES CSc1csc2cc(ccc12)-c1nc([nH]c1-c1ccncc1)-c1ccc(OCCN(C)C)cc1

InChI Key InChIKey=RZBUGBWUBPWOHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490697   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50490697(CHEMBL2336821)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged BRAF V600E mutant expressed in Sf9 cells using GST-tagged MEK1 and ATP as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed