BDBM50491383 CHEMBL2380490

SMILES COc1ccc(NC2=NC(=O)\C(S2)=C\c2cn(nc2-c2ccccc2Cl)-c2ccccc2)c(OC)c1

InChI Key InChIKey=SEKDBIXGZVAYFP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491383   

TargetPolyphenol oxidase 2(White button mushroom)
Bahirji Smarak Mahavidyalaya

Curated by ChEMBL
LigandPNGBDBM50491383(CHEMBL2380490)
Affinity DataKi:  2.91E+4nMAssay Description:Competitive inhibition of mushroom tyrosinase diphenolase activity assessed as L-DOPA conversion to dopachrome by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Bahirji Smarak Mahavidyalaya

Curated by ChEMBL
LigandPNGBDBM50491383(CHEMBL2380490)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed