BDBM50491536 CHEMBL2380867

SMILES Cc1ccc(o1)-c1noc(C)c1-c1ccccc1

InChI Key InChIKey=SXNVEZCCWFOWDA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50491536   

TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 320nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of arachidonic acid-induced TXB2 formation incubated for 5 mins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of collagen-induced TXB2 formation incubated for 5 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed