BDBM50491698 CHEMBL2387426

SMILES COc1ccc(cc1-c1cnc(nc1)N1CCOCC1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C

InChI Key InChIKey=XABGTSAIKICGRS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491698   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50491698(CHEMBL2387426)Copy SMILESCopy InChI

Affinity DataIC50: 1.40nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50491698(CHEMBL2387426)Copy SMILESCopy InChI

Affinity DataIC50: 265nMAssay Description:Inhibition of PDE4B catalytic domain (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL