BDBM50492428 CHEMBL2401934

SMILES COc1ccc2c(c1)oc1ccc(CN3CCN(CC3)c3ccccc3OC)cc1c2=O

InChI Key InChIKey=TYGHMVYMNAHTMO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50492428   

TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50492428(CHEMBL2401934)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenergic receptor in rat cerebral cortex after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50492428(CHEMBL2401934)
Affinity DataKi:  429nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50492428(CHEMBL2401934)
Affinity DataKi:  561nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50492428(CHEMBL2401934)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]5-CT from human 5HT7b receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50492428(CHEMBL2401934)
Affinity DataKi:  1.36E+4nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed