BDBM50492458 CHEMBL2402759

SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cc2ccc(F)cc2)cc1

InChI Key InChIKey=JGCHJYBPEZRKBN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50492458   

TargetCarbonic anhydrase 2(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50492458(CHEMBL2402759)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50492458(CHEMBL2402759)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins to 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50492458(CHEMBL2402759)
Affinity DataKi:  3.90nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Bezmialem Vakif University

Curated by ChEMBL
LigandPNGBDBM50492458(CHEMBL2402759)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50492458(CHEMBL2402759)
Affinity DataKi:  101nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins to 6 hrs by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50492458(CHEMBL2402759)
Affinity DataKi:  101nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 10 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed