BDBM50492572 CHEMBL2407322

SMILES COC(=O)C(C1CCNCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=LWRGZHPFEOLOIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50492572   

TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50492572(CHEMBL2407322)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]-hydroxytryptamine from human SERT expressed in CHO cells by TopCounting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50492572(CHEMBL2407322)
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]-norepinephrine from human NET expressed in CHO cells by TopCounting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50492572(CHEMBL2407322)
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]-dopamine from human DAT expressed in CHO cells by TopCounting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed