BDBM50493411 CHEMBL2425770

SMILES COc1ccc(\C=C\c2ccncc2)c2cc(nn12)C(F)(F)F

InChI Key InChIKey=PRXNNQRBXHRZRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493411   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493411(CHEMBL2425770)
Affinity DataIC50: 15nMAssay Description:Inhibition of core catalytic domains PDE4B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493411(CHEMBL2425770)
Affinity DataIC50: 6.71E+4nMAssay Description:Inhibition of core catalytic domains PDE3A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed