BDBM50494394 CHEMBL3086238

SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(-c2ccccc2)c2C=N[C@@H](c3ccccc3)C(=O)Nc12

InChI Key InChIKey=JNFIBUJYPMYKTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494394   

TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494394(CHEMBL3086238)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed