BDBM50495088 CHEMBL1089495

SMILES ONC(=O)CCCCCCC(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=ZOPUASBAPJLYBB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50495088   

TargetHistone deacetylase 6(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 6nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 63nMAssay Description:Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 75nMAssay Description:Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 113nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 165nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 185nMAssay Description:Inhibition of human HDAC3/NCOR2 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50495088(CHEMBL1089495)
Affinity DataIC50: 374nMAssay Description:Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed