BDBM50495334 CHEMBL3109647
SMILES OC(=O)[C@H]1CC[C@H](Cn2c(=O)n(Cc3cccc(c3C#N)C(F)(F)F)c3ccccc3c2=O)CC1
InChI Key InChIKey=WSTUZGSSQNKRSR-WKILWMFISA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50495334
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human TNKS1 incubated for 30 mins prior to substrate addition measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of human TNKS2 after 1 to 2 hrs by fluorescence polarization methodMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of human TNKS2 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human TNKS2 incubated for 30 mins prior to substrate addition measured after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human TNKS1 incubated for 1 to 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human TNKS1 after 1 to 2 hrs by fluorescence polarization methodMore data for this Ligand-Target Pair