BDBM50495604 CHEMBL3114160

SMILES CC(C)n1cc2c(Cl)nc(nc2n1)N(C(=O)c1ccccc1)C(=O)c1ccccc1

InChI Key InChIKey=OYLWRVXTMMKXNA-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50495604   

TargetAdenosine receptor A2a(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50495604(CHEMBL3114160)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]-NECA from human adenosine A2A receptor expressed in CHO cells after 3 hrs by topcount scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50495604(CHEMBL3114160)
Affinity DataKi:  900nMAssay Description:Binding affinity to human adenosine A3A receptor measured by radioligand-based affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A3(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50495604(CHEMBL3114160)
Affinity DataKi:  6.70E+3nMAssay Description:Displacement of [3H]-HEMADO from human adenosine A3 receptor expressed in CHO cells after 3 hrs by topcount scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50495604(CHEMBL3114160)
Affinity DataKi:  7.90E+3nMAssay Description:Displacement of [3H]-CCPA from human adenosine A1 receptor expressed in CHO cells after 3 hrs by topcount scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50495604(CHEMBL3114160)
Affinity DataKi: >2.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced adenylyl cyclase activity after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed