BDBM50495852 CHEMBL3112596

SMILES CNc1nc(c[nH]1)-c1cccc(NC(=O)c2cc3ccccc3[nH]2)c1

InChI Key InChIKey=UMBIDIUNTWEHKV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50495852   

TargetSodium channel protein type 5 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 2.00E+4nMAssay Description:Modulation of human Nav1.5 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.7 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.3 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.7 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.4 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.4 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.3 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495852(CHEMBL3112596)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.5 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed