BDBM50495870 CHEMBL3113261

SMILES CNc1nc(cn1C(=O)OC(C)(C)C)-c1cccc(NC(=O)c2ccco2)c1

InChI Key InChIKey=LVVGMLWVACRKAD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50495870   

TargetSodium channel protein type 9 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 2.60E+4nMAssay Description:Modulation of human Nav1.7 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.4 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.3 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.3 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.7 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.5 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.4 in closed state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50495870(CHEMBL3113261)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.5 in open-inactivated state assessed as inhibition of inward current after 4 mins by whole-cell electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed