BDBM50496562 CHEMBL3133866

SMILES COc1ccc2[nH]c(cc2c1)C(=O)NCC=CCN1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=XAESEDLRZCTOOM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496562   

TargetD(3) dopamine receptor(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496562(CHEMBL3133866)
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]ABN from human D3 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496562(CHEMBL3133866)
Affinity DataKi:  119nMAssay Description:Displacement of [125I]ABN from human D2 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496562(CHEMBL3133866)
Affinity DataKi:  162nMAssay Description:Displacement of [125I]ABN from human D4 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496562(CHEMBL3133866)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in guinea pig brain membrane after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed