BDBM50498271 CHEMBL3581009

SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1ccc2nc([nH]c2c1)-c1ccc(OCC#C)cc1

InChI Key InChIKey=RMFORDZLPNJVBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498271   

TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498271(CHEMBL3581009)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498271(CHEMBL3581009)
Affinity DataIC50: 5.16E+4nMAssay Description:Inhibition of human DNA topoisomerase-2 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed