BDBM50498273 CHEMBL3581011

SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1ccc2nc([nH]c2c1)-c1ccc(OCCCCCCCCCC#C)cc1

InChI Key InChIKey=IYJAAOHJSFVWHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498273   

TargetDNA topoisomerase 1(Human)
Clemson University

Curated by ChEMBL
LigandPNGBDBM50498273(CHEMBL3581011)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA topoisomerase-1 using supercoiled pBAD-GFPuv plasmid DNA as substrate assessed as prevention of supercoiled DNA template from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed