BDBM50498277 CHEMBL3582058

SMILES OC(=O)C(\O)=C\C(=O)c1cn(Cc2ccc(Cl)cc2)c2ccccc2c1=O

InChI Key InChIKey=IYMHJOBWAFXAAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50498277   

TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50498277(CHEMBL3582058)
Affinity DataIC50: 540nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50498277(CHEMBL3582058)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of 3'-processing activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50498277(CHEMBL3582058)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of RNase H function of HIV1 reverse transcriptase using DNA/RNA hybrid as substrate by fluorescence spectrometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed