BDBM50498568 CHEMBL3609618

SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZASPFNTXFLESNS-PLZPTFKGSA-N

Data  4 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50498568   

TargetSubstance-P receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-substance P from human NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]-substance P from rat NK1 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at rat mu opioid receptor transfected in HN9.10 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at human delta opioid receptor transfected in HN9.10 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataIC50:  180nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50498568(CHEMBL3609618)
Affinity DataIC50:  210nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed