BDBM50498996 CHEMBL3735045

SMILES CC(C)n1c(C)nc2cnc(Nc3ccnc(n3)N3CCC(CC3)S(C)(=O)=O)cc12

InChI Key InChIKey=UMJAMNNZTJYPHO-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498996   

TargetEpidermal growth factor receptor(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50498996(CHEMBL3735045)
Affinity DataKi:  64nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB