BDBM50499177 CHEMBL3736447

SMILES CC[C@H](C)[C@H](NC(=O)c1ccc(OC)cc1OC)c1nc(co1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=VUPOPVAYZAPXSS-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50499177   

TargetC3a anaphylatoxin chemotactic receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50499177(CHEMBL3736447)
Affinity DataEC50:  850nMAssay Description:Agonist activity at C3aR in human MDM cells assessed as inhibition of C3a-induced Ca2+ response measured for 60 secs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC3a anaphylatoxin chemotactic receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50499177(CHEMBL3736447)
Affinity DataEC50:  851nMAssay Description:Agonist activity at C3aR in human MDM cells assessed as inhibition of C3a-induced Ca2+ response measured for 60 secs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC3a anaphylatoxin chemotactic receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50499177(CHEMBL3736447)
Affinity DataIC50: 870nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetC3a anaphylatoxin chemotactic receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50499177(CHEMBL3736447)
Affinity DataIC50: 871nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed