BDBM50499301 CHEMBL3735380

SMILES CC(C)n1nc(C#Cc2cccc(c2)C(F)(F)F)c2c(N)ncnc12

InChI Key InChIKey=GZOUZKNRUVPCDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499301   

TargetTyrosine-protein kinase ABL1(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50499301(CHEMBL3735380)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Abl T315I mutant (unknown origin) after 30 mins by phosphocellulose paper disk assay using 0.1 mM EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50499301(CHEMBL3735380)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human wild-type Abl after 30 mins by phosphocellulose paper disk assay using 0.1 mM EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed