BDBM50499305 CHEMBL3736026

SMILES CC(C)n1nc(C#Cc2cccc(C)c2)c2c(N)ncnc12

InChI Key InChIKey=VTVJWJQBJYROQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499305   

TargetTyrosine-protein kinase ABL1(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50499305(CHEMBL3736026)
Affinity DataIC50: 900nMAssay Description:Inhibition of human wild-type Abl after 30 mins by phosphocellulose paper disk assay using 0.1 mM EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50499305(CHEMBL3736026)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of Abl T315I mutant (unknown origin) after 30 mins by phosphocellulose paper disk assay using 0.1 mM EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed