BDBM50499964 CHEMBL3741896

SMILES OC(=O)[C@H]1CC[C@@H](CC1)Oc1ccc(cc1)C(=O)Nc1nnc(Cc2cc(F)cc(F)c2)s1

InChI Key InChIKey=SBONFSMOJRSALT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499964   

TargetDiacylglycerol O-acyltransferase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499964(CHEMBL3741896)
Affinity DataIC50: 76nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499964(CHEMBL3741896)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed