BDBM50499979 CHEMBL3741016

SMILES OC(=O)[C@@H]1CC[C@@H](CC1)Oc1ccc(cc1)C(=O)Nc1nc(Cc2cc(F)cc(F)c2)no1

InChI Key InChIKey=GJYQGOAKAVMKFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499979   

TargetDiacylglycerol O-acyltransferase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499979(CHEMBL3741016)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499979(CHEMBL3741016)
Affinity DataIC50: 310nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed