BDBM50500959 CHEMBL3799939

SMILES [H][C@@]12CCN(C(=O)CC(C)(C)O)[C@]1([H])C(=O)N(C2)c1cccc2n(ncc12)-c1ccccc1F

InChI Key InChIKey=VGPVZPALXCWXDX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500959   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50500959(CHEMBL3799939)Copy SMILESCopy InChI

Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
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TargetSodium channel protein type 5 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50500959(CHEMBL3799939)Copy SMILESCopy InChI

Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell-patch clamp methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL