BDBM50500962 CHEMBL3798242

SMILES CC(Oc1nn(-c2ccccc2F)c2ccc(F)cc12)C(=O)N1CCOCC1

InChI Key InChIKey=VEUTYUARWSZCHF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500962   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50500962(CHEMBL3798242)Copy SMILESCopy InChI

Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50500962(CHEMBL3798242)Copy SMILESCopy InChI

Affinity DataIC50: 620nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293F cells measured at -65 mV holding potential by Qpatch clamp methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL