BDBM50500965 CHEMBL3799372

SMILES CN1CCN(CCOc2nn(-c3ccccc3F)c3ccc(F)cc23)C1=O

InChI Key InChIKey=MFXGWJILJOSHLE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500965   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50500965(CHEMBL3799372)Copy SMILESCopy InChI

Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

Curated by ChEMBL

LigandBDBM50500965(CHEMBL3799372)Copy SMILESCopy InChI

Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293F cells measured at -65 mV holding potential by Qpatch clamp methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/4/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL