BDBM50501724 CHEMBL4095512

SMILES Cc1cc(\C=C\C#N)cc(C)c1Oc1cc(Nc2ccc(cc2)C#N)c(N)cc1C(=O)OCCC#N

InChI Key InChIKey=CUGXLXTYORXILY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50501724   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Beijing Institute of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50501724(CHEMBL4095512)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of rilpivirine-resistant HIV1 NL4-3 reverse transcriptase E138K mutant infected in human TZM-b1 cells after 2 days by bright Glo-luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed