BDBM50501791 CHEMBL4102053

SMILES Cc1ccccc1CS(=O)(=O)n1c2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=WCTJWSITQMXFGM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50501791   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase p66/p51 RNA-dependent DNA polymerase activity expressed in Escherichia coli JM109 ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase Y181C mutant assessed as reduction in dTTP incorporation using poly(rA)/oligo(dT)16 as template/primer afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase Y188L mutant assessed as reduction in dTTP incorporation using poly(rA)/oligo(dT)16 as template/primer afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase E138K mutant assessed as reduction in dTTP incorporation using poly(rA)/oligo(dT)16 as template/primer afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase K103N mutant assessed as reduction in dTTP incorporation using poly(rA)/oligo(dT)16 as template/primer afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase G190A mutant assessed as reduction in dTTP incorporation using poly(rA)/oligo(dT)16 as template/primer afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50501791(CHEMBL4102053)
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase V106A mutant assessed as reduction in dTTP incorporation using poly(rA)/oligo(dT)16 as template/primer afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed