BDBM50502566 CHEMBL4438626

SMILES O=C(CCCNc1c2c(nc3cc(Cl)ccc13)CCCC2)NC12CC3CC(F)(CC(C1)c1ccccc13)C2

InChI Key InChIKey=TYMUTPUANLZRMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502566   

TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502566BDBM50502566(CHEMBL4438626)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502566BDBM50502566(CHEMBL4438626)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed