BDBM50503123 CHEMBL4545684

SMILES COCc1nc2cc(Cl)ccn2c1Cc1ccc2c(COc3cc(F)ccc3\C2=C(/C)c2noc(=O)[nH]2)c1

InChI Key InChIKey=QZNUPRHBNYAKDD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503123   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50503123(CHEMBL4545684)
Affinity DataEC50:  1nMAssay Description:Agonist activity at PPARgamma in human MKN45 cells assessed as induction of cell aggregation incubated for 5 days by Hoechst 33342 staining based IN ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50503123(CHEMBL4545684)
Affinity DataEC50:  5.30nMAssay Description:Transactivation of chimeric GAL4-fused human PPARgamma transfected in HEK293EBNA cells measured at 24 hrs after drug treatment by steady-Glo lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed