BDBM50503163 CHEMBL4460927

SMILES FC(F)(F)c1cccc2n(CC3CC3)nnc12

InChI Key InChIKey=ZLNSGYSEJVMKQS-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50503163   

TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503163(CHEMBL4460927)
Affinity DataEC50:  148nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503163(CHEMBL4460927)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503163(CHEMBL4460927)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503163(CHEMBL4460927)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503163(CHEMBL4460927)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed