BDBM50503279 CHEMBL4449563

SMILES [H][C@]1(COC(=O)N1c1nc(N[C@H](C)c2cn(cn2)-c2ccc(F)cc2)nc2ccsc12)[C@H](C)O

InChI Key InChIKey=HLITUJBDEYGTOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50503279   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503279(CHEMBL4449563)
Affinity DataIC50: 28nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-KG as substrate after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed