BDBM50503283 CHEMBL4469739

SMILES C[C@@H](Nc1nc(N2[C@H](COC2=O)c2ccccc2)c2cn[nH]c2n1)c1cn(cn1)-c1ccc(Cl)cc1

InChI Key InChIKey=DLAYPPZBDFFXGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50503283   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503283(CHEMBL4469739)
Affinity DataIC50: 28nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-KG as substrate after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed