BDBM50503469 CHEMBL4575990

SMILES NC(=O)c1cc(-c2ccc(F)cc2)n2nc(CCc3ccnc(c3)C(F)(F)F)cc2n1

InChI Key InChIKey=BHWJLGWNJPUSLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503469   

TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503469(CHEMBL4575990)
Affinity DataIC50: 87nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503469(CHEMBL4575990)
Affinity DataIC50: 87nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed