BDBM50503932 CHEMBL4443960

SMILES CC1CCc2cc(F)cc3c(O)c(C(=O)NCc4cccnc4)c(=O)n1c23

InChI Key InChIKey=AIYVCKRQIPKGLQ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50503932   

TargetToll-like receptor 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50503932(CHEMBL4443960)
Affinity DataEC50:  300nMAssay Description:Agonist activity at TLR2 (unknown origin) by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetToll-like receptor 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50503932(CHEMBL4443960)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TLR2 expressed in HEK-Blue cells harboring NFkB promoter-driven secreted alkaline phosphatase assessed as induction of NFkB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50503932(CHEMBL4443960)
Affinity DataEC50:  1.35E+3nMAssay Description:Agonist activity at human TLR2 expressed in HEK cells assessed as induction of MCP1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed