BDBM50504102 CHEMBL4541330

SMILES C=CC(=O)NCc1ccc(-n2nc3c(=O)[nH]nc(N)c3c2-c2oc3ccc(C)cc3c2C)cc1

InChI Key InChIKey=GXIHBWCRCZNSHX-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50504102   

TargetFibroblast growth factor receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human FGFR2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 13nMAssay Description:Inhibition of human FGFR3 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 16nMAssay Description:Inhibition of human FGFR1 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 200nMAssay Description:Inhibition of human FGFR4 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human EPHA2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERbb4 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Ret using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human EGFR using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ALK using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human VEGFR2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERbb2 using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human c-MET using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ABL using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504102BDBM50504102(CHEMBL4541330)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human c-Src using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISA relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed