BDBM50505326 CHEMBL4524437::US20260070878, Compound 173
SMILES COc1cccc2c(=O)[nH]c(-c3ccc(C(C)(C)O)cc3)nc12
InChI Key InChIKey=NGWLKFVMSQZGRO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50505326
Affinity DataIC50: 4.60nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS1 (1023 to 1327 residues) expressed in baculovirus infected sf9 cells assessed...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of GST tagged-TEV cleavage site-fused human recombinant TNKS2 (873 to 1166 residues) expressed in baculovirus infected sf9 cells assessed ...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human full-length Myc/His-tagged Parp-1 expressed in baculovirus infected Sf21 insect cells assessed as reduction in auto-P...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Inhibition of tankyrase 1/2 in human DLD1 cells assessed as increase in axin2 accumulation incubated for 24 hrs by luminex based bead assayMore data for this Ligand-Target Pair