BDBM50505830 CHEMBL4474912
SMILES Oc1c(NC(=O)CCN2CCOCC2)ccc2c(ccnc12)-c1cc2ccccc2o1
InChI Key InChIKey=FOXYYCJUQCUSPX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50505830
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human topoisomerase 2alpha mediated decatenation using kDNA as susbtrate preincubated for 20 mins followed by substrate and ATP additio...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with EcadPro-RFP reporter assessed as reversion of epithelial-mesenchymal tra...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Inhibition of topoisomerase 2alpha in human SW620 organoids transfected with VimPro-GFP reporter assessed as reversion of epithelial-mesenchymal tran...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of topoisomerase 2alpha dependent TCF transcription in human SW620 organoids transduced with TOPflash luminescent reporter after 72 hrs by...More data for this Ligand-Target Pair