BDBM50505852 CHEMBL4538032

SMILES NS(=O)(=O)c1ccc(CCNC(=O)C(=C)Cc2ccccc2Cl)cc1

InChI Key InChIKey=VWOPIJFNGNHCIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505852   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50505852(CHEMBL4538032)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of recombinant human NLRP3 ATPase preincubated for 15 mins followed by ATP addition and measured after 40 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50505852(CHEMBL4538032)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of recombinant human NLRP3 ATPase assessed as reduction in ADP formation preincubated for 10 mins followed by ATP addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50505852(CHEMBL4538032)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of recombinant human NLRP3 ATPase activity preincubated for 15 mins followed by ATP addition measured after 40 mins by ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed