BDBM50506846 CHEMBL4436970

SMILES CN1CCC(CNS(=O)(=O)c2ccc(NC(=O)Nc3ccc(cc3N)C(F)(F)F)cc2)C1

InChI Key InChIKey=VIDXZSKAFIGXIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506846   

TargetGenome polyprotein(Dengue virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506846(CHEMBL4436970)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506846(CHEMBL4436970)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed