BDBM50506850 CHEMBL3971531

SMILES Nc1cc(Cl)ccc1NC(=O)Nc1ccc(cc1)S(=O)(=O)Oc1ccc(cc1)C(O)=O

InChI Key InChIKey=VEPMPOQJMHGPQF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506850   

TargetGenome polyprotein(Dengue virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506850(CHEMBL3971531)
Affinity DataIC50:  3.68E+5nMAssay Description:Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(ZIKV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506850(CHEMBL3971531)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506850(CHEMBL3971531)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of WNV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed