BDBM50506926 CHEMBL4436197

SMILES COc1cccc(c1)[C@@H](CCN1CCOCC1)NC(=O)c1ccc(cc1)-c1ccnc(F)c1

InChI Key InChIKey=RURMYELSAFPPJN-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506926   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50506926(CHEMBL4436197)
Affinity DataIC50:  139nMAssay Description:Inhibition of human GST-tagged catalytic ROCK1 expressed in baculovirus system using STK S2 peptide substrate and and 33P-ATP after 60 mins by HTRF a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50506926(CHEMBL4436197)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST-fused human recombinant ROCK2 (11 to 552 residues) expressed in Spodoptera frugiperda insect cells using STK S2 peptide substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed