BDBM50507211 CHEMBL4444843

SMILES Clc1cc(cc2cc[nH]c12)C(=O)CCC1CCN(CC2CCCCC2)CC1

InChI Key InChIKey=JWNWVBYZLJCIIB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507211   

TargetSigma non-opioid intracellular receptor 1(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507211(CHEMBL4444843)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human Jurkat cell membranes after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507211(CHEMBL4444843)
Affinity DataIC50: 29nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50507211(CHEMBL4444843)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-GR113808 from recombinant human 5-HT4BR expressed in membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed