BDBM50507426 CHEMBL4461978

SMILES OC(=O)CNC(=O)c1c(O)c2COCCc2n(Cc2ccc(nc2)C(F)(F)F)c1=O

InChI Key InChIKey=UUPLODLHSLMEQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507426   

TargetProlyl hydroxylase EGLN2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507426(CHEMBL4461978)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507426(CHEMBL4461978)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50507426(CHEMBL4461978)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed