BDBM50507599 CHEMBL4456952

SMILES COc1ccc(cc1)-c1cc(=O)c2cc(OC)c3cccc(OC)c3c2[nH]1

InChI Key InChIKey=KCQYCVMSWZNNRJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507599   

TargetCytochrome P450 1B1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50507599(CHEMBL4456952)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human CYP1B1 using 7-Ethoxyresorufin as substrate after 30 mins in presence of NADP+ by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50507599(CHEMBL4456952)
Affinity DataIC50: 65nMAssay Description:Inhibition of human CYP1A1 using 7-Ethoxyresorufin as substrate after 15 mins in presence of NADP+ by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Birla Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50507599(CHEMBL4456952)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP1A2 using 7-Ethoxyresorufin as substrate after 50 mins in presence of NADP+ by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed